PD-1 Cooperates with AIRE-Mediated Tolerance to Prevent Lethal Autoimmune Disease

By
Justin.choi
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0
290
Using a range of mouse genetic models, researchers uncovered a critical tolerogenic axis between the autoimmune regulator, AIRE, and the immune checkpoint molecule, PD-1.
[Proceedings of the National Academy of Sciences of the United States of America]

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Abstract