SARS-CoV-2 Infection of Airway Cells Causes Intense Viral and Cell Shedding, Two Spreading Mechanisms Affected by IL-13

To investigate viral spread, primary human airway epithelial cell cultures were infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and host–virus interactions were examined via electron microscopy, immunohistochemistry, RNA in situ hybridization, and gene expression analyses.