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western blot analysis
Intestinal Cell News
Gastric Cancer Cell-Derived Extracellular Vesicles Elevate E2F7 Expression and Activate the MAPK/ERK Signaling to Promote Peritoneal Metastasis through the Delivery of SNHG12
[Cell Death Discovery] Scientists explored the ability of gastric cancer (GC) cell-derived extracellular vesicles (EVs)-mediated microRNA-129-5p/E2F transcription factor 7/mitogen-activated protein kinase/extracellular regulated protein kinase axis to affect the peritoneal metastasis of GC by delivering lncRNA small nucleolar RNA host gene 12.
Hepatic Cell News
Emodin Suppresses Hepatocellular Carcinoma Growth by Regulating Macrophage Polarization via microRNA-26a/Transforming Growth Factor Beta 1/Protein Kinase B
[Bioengineered] After co-culture systems of M2 macrophages and HCC cells were established, it was shown that co-culture with M2 macrophages could promote both the proliferation and invasion of HepG2 and Huh7 cells.
Pancreatic Cell News
Rhoifolin from Plumula Nelumbinis Exhibits Anti-cancer Effects in Pancreatic Cancer via AKT/JNK Signaling Pathways
[Scientific Reports] Cell viability assay revealed that apiin, rhoifolin, and vitexin could inhibit proliferation of PANC-1 and ASPC-1, with rhoifolin showing the maximum inhibitory effect.
Prostate Cell News
GATA Binding Protein 5-Mediated Transcriptional Activation of Transmembrane Protein 100 Suppresses Cell Proliferation, Migration and Epithelial-to-Mesenchymal Transition in Prostate Cancer DU145 Cells
[Bioengineered] The authors uncovered the role of GATA binding protein 5-mediated activation of transmembrane protein 100 in the proliferation, migration and epithelial-to-mesenchymal transition of prostate cancer cells.
Pancreatic Cell News
Sigma-1 Receptor Overexpression Promotes Proliferation and Ameliorates Cell Apoptosis in β-Cells
[Molecular Medicine Reports] The authors investigated the role of sigma‑1 receptor (Sig-1R) in islet β‑cell proliferation and examined the effects of Sig‑1R on islet β‑cell injury under lipotoxic conditions.
Muscle Cell News
Catalpol Protects AC16 Cells from Hypoxia/Reoxygenation Injury by Regulating the miR-22-3p/DPP4 Axis
[Journal of Biochemical and Molecular Toxicology] Catalpol promoted the viability and reduced cell apoptosis of human cardiomyocyte AC16 cells and repressed the release of inflammatory cytokines TNF-α, IL-6, and IL-1β, while inhibiting the leakage of myocardial injury markers lactate dehydrogenase and creatine kinase.