Review

[Blood] Results from genetic mouse models have demonstrated the impact of Adenosine Deaminase Acting on RNAs' catalytic activity on hematopoietic cells, complemented by insights from human cell studies.

[Clinical Reviews In Allergy & Immunology] Given the unique roles and significant contributions of various cell types involved in the process of psoriasis, a thorough analysis of specific epigenetic patterns in different cell types becomes a key entry point for elucidating the mechanisms of disease development.

[Obesity Reviews] Scientists explore recent advances in the generation of stem cell-derived hepatocyte-like cells and insulin-producing β-like cells. They cover the different differentiation strategies, new discoveries, and the caveats that still exist regarding their routine use.

[Bone Research] The authors review the signaling pathways by which brain and muscle arnt-like 1 (Bmal1) regulate bone/cartilage metabolism, the upstream regulatory factors that control Bmal1, and the current Bmal1 knockout mouse models for research.

[Molecular Neurodegeneration] Scientists highlight the significance of lipidomics and lipid-targeting approaches in the diagnosis and treatment of Alzheimer's disease.

[EMBO Molecular Medicine] The authors discuss recent advances in versatile human tonsil/adenoid tissue-based ex vivo immune organoid cultures as well as related cancer and autoimmunity-focused experimental setups.