skeletal muscle cells

[Proceedings of the National Academy of Sciences of the United States of America] Using multiple screening assays upstream and downstream of miR-29a signaling, investigators located the secreted protein and adipogenic inhibitor SPARC to an fibroblast growth factor-2 (FGF-2) signaling pathway that was conserved between skeletal muscle cells from mice and humans and that was activated in skeletal muscle of aged mice and humans.

[Cell Death & Disease] Investigators studied terminally differentiated postmitotic skeletal muscle cells in which oxidative stress induced the dynamic activation of PRC2-Ezh1 through Embryonic Ectoderm Develpment shuttling to the nucleus and identified lncRNA Malat-1 as a necessary partner for PRC2-Ezh1-dependent response to oxidative stress.

[Scientific Reports] The authors investigated whether imbalanced mitochondrial dynamics affected mitochondrial function and bioenergetic efficiency in skeletal muscle cells of Megaconial Congenital Muscular Dystrophy.

[Genome Medicine] Human induced pluripotent stem-derived skeletal muscle cells from a healthy donor and Becker Muscular Dystrophy patients were utilized to study dystrophin in muscular dystrophy post-translational modifications and associated proteins.

[Communications Biology] Scientists showed a xanthene derivative, DS20060511, induced GLUT4 translocation to the skeletal muscle cell surface, thereby stimulating glucose uptake into the tissue.

[Scientific Reports] Honey bee CREs had a larger spatial spread at half maximum than their vertebrate counterparts and a slightly ellipsoidal shape, two characteristics that may be related to ultrastructural features specific to invertebrate cells.