skeletal muscle cells

[Scientific Reports] Researchers performed metabolic profiling of the C2C12 myoblasts and myotubes in serum-free mediums and compared it with conventional serum supplementation culture.

[Nano Convergence] Scientists reported a nano-sized graphene oxide-modified nanopillars on microgroove hybrid polymer array that effectively controlled skeletal muscle cell differentiation.

[Journal of General Physiology] ATP release occurs in two peaks, the first around 15 s after electrical stimulation (ES) and a second around 300 s after ES. Researchers used apyrase to hydrolyze ATP 60 s after ES, maintaining the first peak and eliminating the second peak.

[Microsystems & Nanoengineering] Investigators presented a simple strategy for using optical media discs with nanogrooves and other polymer-based substrates nanomolded from the discs to directly culture muscle cells to study their response to the effect of biophysical cues such as nanotopography and substrate stiffness.

[Scientific Reports] Researchers measured changes in mechanistic target of rapamycin complex 1 signaling, the ubiquitin–proteasome system, and autophagy-lysosome system-related factors after a single intramuscular injection of MSCs with green fluorescence protein into mouse muscles.

[Nature Communications] Scientists showed that overexpression of miR-19b-3p in human skeletal muscle cells increased insulin signaling, glucose uptake, and maximal oxygen consumption, recapitulating the adaptive response to aerobic exercise training.