pulmonary cells

[Thoracic Cancer] Inhibition of progression of lung cancer cells induced by heterogeneous nuclear ribonucleoprotein K-knockdown was dependent on activation of p53 by the p53/p21/cyclin D1 pathway.

[Cancer Immunology Immunotherapy] In an in vitro study using lung cancer cell lines and human monocyte-derived macrophages, the conditioned medium from cancer cells was found to up-regulate programmed cell death-1 ligand 1 expression on macrophages via STAT3 activation.

[Oxidative Medicine and Cellular Longevity] Scientists explored the effect of the plasma-activated medium on lung cancer cells in vitro and in vivo by using a 3D cell culture model.

[Nature Communications] The authors reported that vaccinia C7 was a crucial virulence factor that blocked activation of the transcription factor IRF3.

[Science Advances] Researchers uncovered that the depletion of ARAF promoted anchorage-independent growth and metastasis through activation of AKT signaling in a subset of lung cancer cells.

[Immunology & Cell Biology] Researchers presented a laboratory model to characterize responses of differentiated airway epithelium and neutrophils following respiratory infection.