publication

Investigators explored the role of CSCs in lymph node metastasis of oral squamous cell carcinoma, focusing on the expression and biological significance of nuclear receptor subfamily 2 group F member 2...

Researchers revealed that PKCλ-dependent asymmetric division of ALDH1-positive CSCs led to an uneven distribution of glycolytic capacity, which was crucial for understanding metabolic heterogeneity within a tumor. [Scientific Reports] Full Article

Researchers observed that non-structural maintenance of chromosomes condensin I complex subunit H (NCAPH) expression was upregulated in ovarian cancer cells. Silencing NCAPH led to repression of both stemness characteristics and glucose...

[Osteogenesis] Investigators characterized bone-marrow MSCs mitochondrial fitness, bioenergetics, and dynamics with a focus on therapeutics.

Scientists established the fatty acid binding protein 7 (Fabp7)-knockout B16F10 melanoma cells, which showed an enhanced invasion through matrix-coated membrane, without significant change in proliferation. [Scientific Reports] Full Article

Investigators explored liver TET1 in metabolic dysfunction-associated steatotic liver disease (MASLD) progression. Depleting TET1 using two different strategies substantially alleviated MASLD progression. [EMBO Molecular Medicine] Full ArticleGraphical Abstract