protein kinase B

[Bioengineered] The prostatic epithelial cell RWPE-1 and prostate cancer cell DU145 were exposed to Fraxetin to detect the changes in cell viability using cell counting kit-8 assay.

[Bioengineered] After co-culture systems of M2 macrophages and HCC cells were established, it was shown that co-culture with M2 macrophages could promote both the proliferation and invasion of HepG2 and Huh7 cells.

[Cell Death & Disease] The inhibitory effect of Selenoprotein S (SelS) on hepatic steatosis and insulin resistance was confirmed by SelS overexpression in primary hepatocytes in vitro.

[Scientific Reports] Investigators discovered a mechanical correlation between leucine proline-enriched proteoglycan 1 (LEPRE1) and pelitinib drug sensitivity using in silico statistical methods and confirmed the correlation in acute myeloid leukemia and A549 lung cancer cells.

[Scientific Reports] Using in silico and in vitro techniques, investigators demonstrated heterogeneous expression of CD97, a leukocyte adhesion marker, in human glioblastoma.

[Biomedicine & Pharmacotherapy] Decursin exhibited no cytotoxicity and significantly reduced intracellular tyrosinase activity and melanin content in B16F10 melanoma cells.