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protein expression

CircRBM33 Downregulation Inhibits Hypoxia-Induced Glycolysis and Promotes Apoptosis of Breast Cancer Cells via a MicroRNA-542-3p/HIF-1α Axis

[Cell Death Discovery] Breast cancer clinical tissue samples were collected to test differential expressions of circRBM33, miR-542-3p, and HIF-1α. MCF-7 cells were subjected to normoxia or hypoxia and transfected with plasmids that regulated CircRBM33, miR-542-3p, and HIF-1α expression levels.

Adipose Stem Cell-Derived Extracellular Vesicles Ameliorates Corticosterone-Induced Apoptosis in the Cortical Neurons via Inhibition of ER Stress

[Stem Cell Research & Therapy] To investigate neuroprotection effects of adipose stem cell-derived extracellular vesicles in the corticosterone (CORT)-induced cortical neurons, scientists cultured cortical neurons from E15 mice for 7 days, and the cultured cortical neurons were pretreated with different numbers for 30 min followed by administration of 200 μM CORT for 24 hours.

Major Histocompatibility Complex Class I Molecule Expression by Pancreatic Cancer Cells Is Regulated by Activation and Inhibition of the Epidermal Growth Factor Receptor

[Immunologic Research] In this current study, the authors discovered that epidermal growth factor receptor affected major histocompatibility complex class I mRNA and protein expression by human pancreatic cancer cell lines.

Sigma-1 Receptor Overexpression Promotes Proliferation and Ameliorates Cell Apoptosis in β-Cells

[Molecular Medicine Reports] The authors investigated the role of sigma‑1 receptor (Sig-1R) in islet β‑cell proliferation and examined the effects of Sig‑1R on islet β‑cell injury under lipotoxic conditions.

CircOAS3 Regulates Keratinocyte Proliferation and Psoriatic Inflammation by Interacting with Hsc70 via the JNK/STAT3/NF-κB Signaling Pathway

[Inflammation] Investigators found that circular RNA OAS3 (circOAS3) expression was significantly upregulated in both psoriatic tissues and M5-induced keratinocytes.

MicroRNA-98-5p Inhibits IL-13-Induced Proliferation and Migration of Human Airway Smooth Muscle Cells by Targeting RAC1

[Inflammation] Investigators focused on how miR-98-5p functioned in the proliferation and migration of human airway smooth muscle cells treated with interleukin-13 (IL-13).

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