Tag results:
protein expression
Mammary Cell News
CircRBM33 Downregulation Inhibits Hypoxia-Induced Glycolysis and Promotes Apoptosis of Breast Cancer Cells via a MicroRNA-542-3p/HIF-1α Axis
[Cell Death Discovery] Breast cancer clinical tissue samples were collected to test differential expressions of circRBM33, miR-542-3p, and HIF-1α. MCF-7 cells were subjected to normoxia or hypoxia and transfected with plasmids that regulated CircRBM33, miR-542-3p, and HIF-1α expression levels.
Neural Cell News
Adipose Stem Cell-Derived Extracellular Vesicles Ameliorates Corticosterone-Induced Apoptosis in the Cortical Neurons via Inhibition of ER Stress
[Stem Cell Research & Therapy] To investigate neuroprotection effects of adipose stem cell-derived extracellular vesicles in the corticosterone (CORT)-induced cortical neurons, scientists cultured cortical neurons from E15 mice for 7 days, and the cultured cortical neurons were pretreated with different numbers for 30 min followed by administration of 200 μM CORT for 24 hours.
Pancreatic Cell News
Major Histocompatibility Complex Class I Molecule Expression by Pancreatic Cancer Cells Is Regulated by Activation and Inhibition of the Epidermal Growth Factor Receptor
[Immunologic Research] In this current study, the authors discovered that epidermal growth factor receptor affected major histocompatibility complex class I mRNA and protein expression by human pancreatic cancer cell lines.
Pancreatic Cell News
Sigma-1 Receptor Overexpression Promotes Proliferation and Ameliorates Cell Apoptosis in β-Cells
[Molecular Medicine Reports] The authors investigated the role of sigma‑1 receptor (Sig-1R) in islet β‑cell proliferation and examined the effects of Sig‑1R on islet β‑cell injury under lipotoxic conditions.
Dermal Cell News
CircOAS3 Regulates Keratinocyte Proliferation and Psoriatic Inflammation by Interacting with Hsc70 via the JNK/STAT3/NF-κB Signaling Pathway
[Inflammation] Investigators found that circular RNA OAS3 (circOAS3) expression was significantly upregulated in both psoriatic tissues and M5-induced keratinocytes.
Muscle Cell News
MicroRNA-98-5p Inhibits IL-13-Induced Proliferation and Migration of Human Airway Smooth Muscle Cells by Targeting RAC1
[Inflammation] Investigators focused on how miR-98-5p functioned in the proliferation and migration of human airway smooth muscle cells treated with interleukin-13 (IL-13).