protein expression

[iScience] Knockdown of betacellulin inhibited the growth of EGFR-mutant human lung adenocarcinoma cells in culture and their tumor-forming ability in mice.

[Acta Pharmacologica Sinica] Alcohol dehydrogenase 1C (ADH1C) was first identified as a target gene closely associated with the development of CRC by the comprehensive application of transcriptomics, proteomics, metabonomics and in silico analysis.

[Thoracic Cancer] Inhibition of progression of lung cancer cells induced by heterogeneous nuclear ribonucleoprotein K-knockdown was dependent on activation of p53 by the p53/p21/cyclin D1 pathway.

[Biochemical Pharmacology] Investigators proposed a mechanism by which hydroquinone induced the malignant progression of chronic myeloid leukemia cells.

[Communications Biology] Researchers reported that autophagy affected differently the response of prostate cancer cell lines to olaparib depending on its activation status.

[Immunity] Researchers used single-cell ECCITE-seq, which captures surface protein expression, cellular transcriptome, HIV-1 RNA, and TCR sequences within the same single cell to track clonal expansion dynamics in longitudinally archived samples from six HIV-1-infected individuals and two uninfected individuals.