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protein expression

Nrf2 and NF-κB/NLRP3 Inflammasome Pathways Are Involved in Prototheca bovis Infections of Mouse Mammary Gland Tissue and Mammary Epithelial Cells

[Free Radical Biology and Medicine] Investigators characterized how Prototheca bovis induced inflammatory responses in mouse mammary gland tissue and mammary epithelial cells.

Dinaciclib Inhibits the Stemness of Two Subtypes of Human Breast Cancer Cells by Targeting the FoxM1 and Hedgehog Signaling Pathway

[Oncology Reports] Investigators aimed to examine the stemness‑inhibitory effects of dinaciclib in MCF‑7 and HCC‑1806 breast cancer cells.

Methionine Restriction Enhances the Chemotherapeutic Sensitivity of Colorectal Cancer Stem Cells by miR-320d/C-myc Axis

[Molecular and Cellular Biochemistry] The combined chemotherapy with methionine restriction could enhance the chemotherapeutic sensitivity of colorectal cancer stem cells by up-regulation of miR-320d to inhibit c-Myc expression

Exosomal HMGA2 Protein from EBV-Positive NPC Cells Destroys Vascular Endothelial Barriers and Induces Endothelial-to-Mesenchymal Transition to Promote Metastasis

[Cancer Gene Therapy] Investigators showed that exosomes from Epstein-Barr virus (EBV)-positive nasopharyngeal carcinoma (NPC) cells, but not exosomes from EBV-negative NPC cells, destroyed endothelial cell tight junction proteins, which are natural barriers against metastasis, and promoted endothelial-to-mesenchymal transition in endothelial cells.

Gastric Cancer Cell-Derived Extracellular Vesicles Elevate E2F7 Expression and Activate the MAPK/ERK Signaling to Promote Peritoneal Metastasis through the Delivery of SNHG12

[Cell Death Discovery] Scientists explored the ability of gastric cancer (GC) cell-derived extracellular vesicles (EVs)-mediated microRNA-129-5p/E2F transcription factor 7/mitogen-activated protein kinase/extracellular regulated protein kinase axis to affect the peritoneal metastasis of GC by delivering lncRNA small nucleolar RNA host gene 12.

CircRPAP2 Regulates the Alternative Splicing of PTK2 by Binding to SRSF1 in Breast Cancer

[Cell Death Discovery] The authors presented the first report that circular RNA RPAP2 (circRPAP2) was downregulated in breast cancer tissue samples and cell lines.

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