prostate cells

[Cell Reports] Via genome-scale CRISPR-Cas9 screening, scientists identified protein arginine methyltransferase 1 (PRMT1) as a critical mediator of androgen receptor expression and signaling.

[andrology] The authors determined the influence of macrophage Trichomonas vaginalis macrophage migration inhibitory factor on prostate epithelial cells and its preliminary mechanism.

[Daru-Journal of Pharmaceutical Sciences] Scientists analyzed the phytochemistry and screen the cytotoxic activity of new bioactive compounds against a panel of cancer cells, in addition to proapototic properties against prostate cancer cells.

[Aging] Investigators administrated Qi Ling (QL) to rats and collected the serum from QL-treated rats and established the co-culture system of tumor-associated macrophages/paclitaxel resistant prostate cancer cells.

[Journal of Pineal Research] The authors revealed that melatonin concentration-dependently decreased the migratory and invasive abilities of two osteoblastic prostate cancer cell lines by inhibiting FAK, c-Src and NF-κB transcriptional activity via the melatonin MT1 receptor, which effectively inhibited integrin α2β1 expression.

[Journal of Translational Medicine] The effects of UAP1-like-1 (UAP1L1) on prostate cancer were investigated by detecting the proliferation, migration, invasion and apoptosis of prostate cancer cells in vitro using MTT, wound healing, Transwell and flow cytometry assay, and the tumor growth in vivo.