p65

[Environmental Toxicology] Researchers investigated the effects of glyphosate-based herbicides on antioxidant capacity, inflammatory cytokines, and autophagy of porcine intestinal epithelial cells IPEC-J2 and its molecular mechanism.

[Oncogene] The authors evidenced that cholesterol promoted cell proliferation and invasion of lung adenocarcinoma (LAC) in vitro as well as LAC metastasis in vivo.

[Cell Death & Disease] Researchers demonstrated that a positive correlation of protein arginine methyltransferase 5 (PRMT5) expression and trimethylamine N-oxide (TMAO)-induced vascular inflammation, with upregulated vascular cell adhesion molecule-1 expression in primary rat and human vascular smooth muscle cells in vitro.

[Journal of Nanobiotechnology] A nanocomposite-based hydrogel was constructed by loading methotrexate into ZnO/Ag to realize combined multiple target therapy of psoriasis.

[British Journal of Dermatology] Investigators showed that microRNA-378a (miR-378a) was induced by IL-17A in keratinocytes through NF-κB, C/EBP-β and IκBζ, and was overexpressed in psoriasis epidermis.

[Scientific Reports] The authors explored the anti-inflammatory effects and underlying molecular mechanism of povidone-iodine (PVP-I) on lipopolysaccharide-stimulated airway epithelial cells and investigated whether nasal instillation of PVP-I could suppress mucosal inflammation in non-eosinophilic chronic rhinosinusitis mice.