p21

[Nature Communications] Scientists reported that pumolio homolog 1 (Pum1) and Pum2 displayed increased expression in human colorectal cancer.

[Cancer Gene Therapy] Scientists revealed that the expression of ALKBH5 was increased in NSCLC and increased expression of ALKBH5 worsened the prognosis of patients with NSCLC.

[Cell Death & Disease] Researchers found that the expression of CMTM6 was significantly reduced in HCC and predicted better prognosis of HCC patients. Through in vitro and in vivo experiments, CMTM6 was shown to inhibit the proliferation of HCC cells by blocking the G1/S phase transition.

[Cell Death & Disease] Scientists found that decreases in N6AMT1 correlated with the extent of DNA N6-methyladenosine (6mA) in clinical breast cancer (BC) tissues and predicted a worse survival of BC patients.

[Bioengineered] Scientists found that in oxidized low-density lipoprotein-treated HUVECs, the increased production of total cholesterol, free cholesterol, and pro-inflammatory cytokines were observed, reversed by 10 μM and 25 μM Nintedanib.

[Proceedings of the National Academy of Sciences of the United States of America] Investigators found that BEND3 was highly expressed in PSCs, and the induction of differentiation resulted in the down-regulation of BEND3.