osteogenic differentiation

[Stem Cell Research & Therapy] The authors fabricated a multilayered nanocomposite scaffold containing the wild type of Type I collagen (Col I) with endogenous magnetic property to promote osteogenesis in rat adipose-derived stem cells with the minimum requirement of osteogenic differentiation medium.

[Experimental and Molecular Medicine] To identify MSC subpopulations and clarify their relationships, scientists performed cell mapping of bone marrow-derived MSCs through single-cell RNA sequencing.

[Bone Research] Scientists reported that circular RNA (circRNA) Stag1 was a critical osteoporosis-related circRNA that showed significantly downregulated expression in osteoporotic bone marrow MSCs and clinical bone tissue samples from patients with osteoporosis.

[Journal of Biomaterials Science-Polymer Edition] Scientists review the potential of synthetic electrospun scaffolds in osteogenic differentiation of iPSCs and address approaches to improve the osteogenic differentiation of these scaffolds.

[Journal of Cellular Biochemistry] Scientists investigated the decoy receptor osteoprotegerin axis and determined the effect of exendin-4 upon adipose MSC osteogenic differentiation.

[Bone Research] Researchers found that the RNA-binding protein Musashi2 regulated bone marrow MSCs (BMSCs) lineage commitment and found that its expression was downregulated during adipogenic differentiation and upregulated during osteogenic differentiation of BMSCs.