Tag results:
melanoma
Human Immunology News
PD-L1 and ICOSL Discriminate Human Secretory and Helper Dendritic Cells in Cancer, Allergy and Autoimmunity
[Nature Communications] Researchers showed, by using 16 different stimuli in vitro, that activated dendritic cells in human blood were phenotypically and functionally dichotomous, and pure cultures of type 2 conventional dendritic cells acquired these states upon appropriate stimuli.
Human Immunology News
Carbon Monoxide Activates PERK-Regulated Autophagy to Induce Immunometabolic Reprogramming and Boost Anti-Tumor T Cell Function
[Cancer Research] The authors used carbon monoxide, a short-lived gaseous molecule, to test if engaging moderate endoplasmic reticulum stress conditions could improve mitochondrial and anti-tumor functions in T cells.
Human Immunology News
Carbon Monoxide Activates PERK-Regulated Autophagy to Induce Immunometabolic Reprogramming and Boost Anti-Tumor T Cell Function
[Cancer Research] The authors used carbon monoxide, a short-lived gaseous molecule, to test if engaging moderate endoplasmic reticulum stress conditions could improve mitochondrial and anti-tumor functions in T cells.
Dermal Cell News
STAG2 Regulates Interferon Signaling in Melanoma via Enhancer Loop Reprogramming
[Nature Communications] Scientists showed that depletion of stromal antigen 2 (STAG2) in melanoma cells led to the expansion of topologically associating domains and enhanced the formation of acetylated histone H3 lysine 27.
Dermal Cell News
A Noncoding Regulatory RNA Gm31932 Induces Cell Cycle Arrest and Differentiation in Melanoma via the MiR-344d-3-5p/Prc1 (and Nuf2) Axis
[Cell Death & Disease] Integrative analysis of whole transcriptome sequencing data demonstrated that lncRNA-Gm31932 was significantly decreased in all-trans retinoic acid-induced and sodium 4-phenylbutanoate-induced mouse melanoma B16 cells.
Dermal Cell News
Low-Metastatic Melanoma Cells Acquire Enhanced Metastatic Capability via Exosomal Transfer of MiR-199a-1-5p from Highly Metastatic Melanoma Cells
[Cell Death Discovery] Scientists showed that exosomal crosstalk between metastatic cancer cells was a new mechanism that underlied cancer metastasis and heterogeneity.