lupus

[Journal of Experimental Medicine] Investigators showed that monocytes acquired macrophage markers upon glomerulonephritis and may have been derived from CCR2+CX3CR1+ double-positive monocytes, which were preferentially recruited, dwelled within glomerular capillaries, and acquired proinflammatory characteristics in the nephritic kidney.

[Journal of Experimental Medicine] Investigators showed that monocytes acquired macrophage markers upon glomerulonephritis and may have been derived from CCR2+CX3CR1+ double-positive monocytes, which were preferentially recruited, dwelled within glomerular capillaries, and acquired proinflammatory characteristics in the nephritic kidney.

[Nature Reviews Rheumatology] Researchers discuss factors that contribute to cardiovascular disease in systemic lupus erythematosus (SLE), with particular focus on how endothelial function and Endothelial progenitor cells (EPCs) are evaluated currently, and how EPCs are quantitatively and functionally altered in patients with SLE.

[Heliyon] The authors indicated that Nigella sativa L. had an immunomodulatory effect and could prevent kidney injury pristane induced Lupus-treated mice.

[Journal of Human Hypertension] Investigators suggested that first-line immunomodulatory therapies prescribed to systemic lupus erythematosus patients would have a beneficial impact on blood pressure.

[Science] Researchers demonstrated mux-seq as a systematic approach to characterize cellular composition, identify transcriptional signatures, and annotate genetic variants associated with systemic lupus erythematosus.