histone acetylation

[EMBO Journal] Scientists provided novel insights into HSC regulation during regeneration by focusing on mitochondrial metabolism and ATP citrate lyase.

[Cancer Research] Researchers described a mechanism by which CAF-secreted lactate was able to increase the expression of genes involved in lipid metabolism in prostate cancer cells.

[Journal of Applied Toxicology] The authors review currently available information on lead (Pb)-mediated alterations in the fetal epigenome is summarized.

[Cell Reports] Scientists performed chromatic immunoprecipitation sequencing ChIP-seq on cerebellum from spinocerebellar ataxia type 7 mice and observed increased H3K9-promoter acetylation in DNA repair genes, resulting in increased expression.

[Nature Communications] Investigators investigated the contributions of chromatin regulatory complexes to fusion positive RMS (FP-RMS) tumor maintenance. They defined the mSWI/SNF functional repertoire in FP-RMS.

[Cell Death & Differentiation] The authors identified mitogen-activated protein kinase kinase 6 as a chromatin relaxer and found that it could significantly enhance reprogramming.