Tag results:

hepatocytes

Citrullination of Glucokinase Is Linked to Autoimmune Diabetes

[Nature Communications] Researchers showed the citrullination of pancreatic glucokinase as a result of inflammation, triggering autoimmunity and affecting glucokinase biological functions.

Disclosing the Antitumor Potential of the Marine Bromoditerpene Sphaerococcenol A on Distinct Cancer Cellular Models

[Biomedicine & Pharmacotherapy] Sphaerococcenol A capacity to impact colorectal-CSCs tumorspheres was evaluated by determining tumorspheres viability, number, and area, as well as the proteasome inhibitory activity.

GITR/GITRL Reverse Signaling Modulates the Proliferation of Hepatic Progenitor Cells by Recruiting ANXA2 to Phosphorylate ERK1/2 and Akt

[Cell Death & Disease] The authors identified reverse signaling between glucocorticoid-induced tumour necrosis factor receptor (GITR) and its ligand (GITRL) as a cross-interaction pathway between immune cells and hepatic stem/progenitor cells that restricted the expansion of hepatic stem/progenitor cells and reduced the possibility of carcinogenesis.

Specification of Fetal Liver Endothelial Progenitors to Functional Zonated Adult Sinusoids Requires C-maf Induction

[Cell Stem Cell] Scientists studied heterogeneity of hepatic vascular cells during mouse development through functional and single-cell RNA-sequencing.

In Vitro Ballooned Hepatocytes Can Be Produced by Primary Human Hepatocytes and Hepatic Stellate Cell Sheets

[Scientific Reports] Researchers engineered cell sheets to develop a new in vitro model of ballooned hepatocytes.

Therapeutic Targeting of Stromal-Tumor HGF-cMET Signaling in an Organotypic Triple Negative Breast Tumor Model

[Molecular Cancer Research] Scientists found that cancer-associated fibroblasts predominantly secreted hepatocyte growth factor (HGF) and activated MET receptor tyrosine kinase in TNBC cells.

Popular