hepatitis

[Cancer Cell International] The authors summarize the biogenesis, characterization and biological functions, recent detection and identification technologies of circRNA, and regulation network mechanism of circRNA in liver diseases

[Open Biology] Scientists developed a CD8+ T cell and adult stem cell liver organoid system using a microfluidic chip to coculture 3D human liver organoids embedded in extracellular matrix with HLA-matched primary human T cells in suspension.

[Science Translational Medicine] The authors characterized blood samples collected from 51 preterm infants longitudinally at five time points, 20 healthy term infants at birth and age 3 to 16 weeks, and five healthy adults, and observed strong associations between type 2 immune polarization in circulating CD3+CD4+ T cells and cardiopulmonary illness, with odds ratios up to 24.

[Liver International] Scientists summarize the current literature on the impact of hepatitis D virus (HDV) in HCC development and discuss the potential interplay between hepatitis B, HDV and neighboring liver tissue in liver carcinogenesis.

[Hepatology] Scientists tested persons for anti-HBs levels 35 years after receiving the primary series. Those with levels under 10 mIU/ml received one booster dose of recombinant hepatitis B vaccine two-four weeks later and were then evaluated on the basis of anti-HBs measurements 30 days post-booster.

[Pharmacological Research] Investigators summarize immuno-modulating drug-induced HBVr during rheumatoid therapy and its preventive strategies for hepatitis B virus reactivation-induced liver diseases, especially cirrhosis and HCC.