Tag results:
hepatic cells
Hepatic Cell News
HucMSC-Derived Exosomes Delivered BECN1 Induces Ferroptosis of Hepatic Stellate Cells via Regulating the xCT/GPX4 Axis
[Cell Death & Disease] Researchers studied the proferroptosis effect and mechanism of mesenchymal stem cell-ex in hepatic stellate cells.
Hepatic Cell News
Blocked Metabotropic Glutamate Receptor 5 Enhances Chemosensitivity in Hepatocellular Carcinoma and Attenuates Chemotoxicity in the Normal Liver by Regulating DNA Damage
[Cancer Gene Therapy] The authors investigated the differential regulatory effect of metabotropic glutamate receptor 5 on chemosensitivity in HCC and chemotoxicity to the normal liver.
Human Immunology News
Citrullination of Glucokinase Is Linked to Autoimmune Diabetes
[Nature Communications] Researchers showed the citrullination of pancreatic glucokinase as a result of inflammation, triggering autoimmunity and affecting glucokinase biological functions.
Cancer Stem Cell News
Disclosing the Antitumor Potential of the Marine Bromoditerpene Sphaerococcenol A on Distinct Cancer Cellular Models
[Biomedicine & Pharmacotherapy] Sphaerococcenol A capacity to impact colorectal-CSCs tumorspheres was evaluated by determining tumorspheres viability, number, and area, as well as the proteasome inhibitory activity.
Hepatic Cell News
GITR/GITRL Reverse Signaling Modulates the Proliferation of Hepatic Progenitor Cells by Recruiting ANXA2 to Phosphorylate ERK1/2 and Akt
[Cell Death & Disease] The authors identified reverse signaling between glucocorticoid-induced tumour necrosis factor receptor (GITR) and its ligand (GITRL) as a cross-interaction pathway between immune cells and hepatic stem/progenitor cells that restricted the expansion of hepatic stem/progenitor cells and reduced the possibility of carcinogenesis.
Endothelial Cell News
Specification of Fetal Liver Endothelial Progenitors to Functional Zonated Adult Sinusoids Requires C-maf Induction
[Cell Stem Cell] Scientists studied heterogeneity of hepatic vascular cells during mouse development through functional and single-cell RNA-sequencing.