hedgehog signaling

[Oncology Reports] Investigators aimed to examine the stemness‑inhibitory effects of dinaciclib in MCF‑7 and HCC‑1806 breast cancer cells.

[Nature Communications] Investigators found that the ability of muscle stem cells to regenerate was regulated by the primary cilium, a cellular protrusion that served as a sensitive sensory organelle.

[Advances in Therapy] The authors analyze and discuss the novel therapies for advanced basal cell carcinoma and squamous cell carcinoma to obtain a sharper perspective of the available treatment options.

[Science Advances] Using an immune “hot” mouse ovarian cancer model, scientists found that cancer-associated-MSCs drove CD8+ T cell tumor immune exclusion and reduced response to anti–PD-L1 immune checkpoint inhibitor via secretion of numerous chemokines.

[Diabetes Research and Clinical Practice] Scientists illustrated the molecular mechanisms by which Forkhead box M1 (FOXM1) enhanced M2 polarization and wound healing of diabetic foot ulcer.

[Nature Communications] Investigators showed that N1-methyladenosine methylation in tRNA was remarkably elevated in hepatocellular carcinoma patient tumor tissues.