gene knockdown

[Neuro-Oncology] Researchers screened a library of drugs either FDA-approved or in clinical trial using a library of patient-derived H3K27M-mutant diffuse midline glioma cell lines with cell viability as the outcome.

[British Journal of Cancer] Plumbagin showed higher blood-brain barrier penetration ability than that of lapachol and shikonin and elicited significant growth inhibitory effects in vitro and in vivo.

[Cell Death & Disease] Researchers studied the proferroptosis effect and mechanism of mesenchymal stem cell-ex in hepatic stellate cells.

[Naunyn-Schmiedebergs Archives of Pharmacology] Scientists discuss the advancement of PCSK9 research on its role and underlying mechanisms in tumor development and progression.

[Phytomedicine] Researchers employed MiaPaCa-2 and PANC-1 cell lines and investigated how urokinase-plasmin activator (uPA) regulated epithelial-mesenchymal transition and metastasis in pancreatic cancer, and presented a novel approach aimed at inhibiting uPA in pancreatic cancer.

[Stem Cell International] Expression of SCRG1 was detected in umbilical cord-derived MSCs by quantitative reverse transcription polymerase chain reaction and immunohistochemical analysis during chondrogenic differentiation.