fibroblasts

[Small] A hemostatic and anti-inflammatory hydrogel patch is designed for promoting diabetic wound healing, derived from dual-cross-linked methacryloyl-substituted Bletilla Striata polysaccharide and gelatin via ultraviolet light.

[Pigment Cell & Melanoma Research] Researchers performed histology and immunohistochemistry analyses and demonstrated that a newly developed full-thickness 3D reconstructed human pigmented skin model and an epidermis-only model exhibit dispersed pigment throughout keratinocytes in the epidermis.

[Seminars in Cell & Developmental Biology] The authors describe the plasticity of dermal fibroblasts (dFBs) during development and wound healing and how various dFB-derived extracellular matrix (ECM) molecules, and in turn how these ECM molecules play a role in regulating the function of dFBs and immune cells.

[Science Signaling] The authors found that glucocorticoid receptor was present in cytoplasmic KRAS-containing complexes and inhibited the activation of wild-type and oncogenic KRAS in mouse embryonic fibroblasts and human lung cancer A549 cells.

[Journal of Cell Science] Cultured progenitor cells established from primary hepatocytes of Pkdcc knockout mice produced a secretome, which promoted their own proliferation in 3D spheroids and proliferation of cultured fibroblasts.

[Advanced Healthcare Materials] The authors presented a method for inducing controlled tumor angiogenesis by engineering the microenvironment that could aid in the development of effective anticancer drugs and cancer immunotherapy.