extracellular matrix

[Biotechnology Journal] Scientists demonstrated a simple method to perform layer by layer assembly on microcarriers to create multilayers of heparin and collagen and further demonstrated that these multilayers had a positive effect on human MSC viability after 48 hours of culture.

[Cancer Science] Researchers observed that cell migration-inducing protein (CEMIP) upregulation facilitated ferroptosis resistance during ECM detachment by promoting cystine uptake in prostate cancer cells.

[Cell and Tissue Research] Investigators investigated the potential of using a selective HDAC2 and 3 inhibitor, MI192, to promote human dental pulp stromal cells bone-like tissue formation in vitro and in vivo within porous Bombyx Mori silk scaffolds.

[JCI Insight] Researchers determined the anti-fibrotic efficacy and potential mechanisms of bromodomain and extra-terminal domain proteins inhibition in systemic sclerosis.

[Cell Death & Disease] Researchers investigated the functional subsets of γδ T cells in hepatic fibrosis and to further explore the underlying causes and drivers of migration.

[Biofabrication] Scientists developed endothelial cell-laden pro- and anti-angiogenic bioinks, supplemented with bioactive matrix-derived microfibers that were created from type I collagen sponges and cartilage decellularized ECM.