endothelial cells

[Oncogene] Liver-specific overexpression of GRB2-associated-binding protein 2 (Gab2) mice accelerated hepatoma progression possibly through activating IL-6-initiated the activation of myeloid-derived suppressor cells.

[Journal of Experimental Medicine] Investigators showed that monocytes acquired macrophage markers upon glomerulonephritis and may have been derived from CCR2+CX3CR1+ double-positive monocytes, which were preferentially recruited, dwelled within glomerular capillaries, and acquired proinflammatory characteristics in the nephritic kidney.

[Oncogene] Liver-specific overexpression of GRB2-associated-binding protein 2 (Gab2) mice accelerated hepatoma progression possibly through activating IL-6-initiated the activation of myeloid-derived suppressor cells.

[Journal of Experimental Medicine] Investigators showed that monocytes acquired macrophage markers upon glomerulonephritis and may have been derived from CCR2+CX3CR1+ double-positive monocytes, which were preferentially recruited, dwelled within glomerular capillaries, and acquired proinflammatory characteristics in the nephritic kidney.

[Nature Reviews Rheumatology] Researchers discuss factors that contribute to cardiovascular disease in systemic lupus erythematosus (SLE), with particular focus on how endothelial function and Endothelial progenitor cells (EPCs) are evaluated currently, and how EPCs are quantitatively and functionally altered in patients with SLE.

[Cancer Gene Therapy] Investigators showed that exosomes from Epstein-Barr virus (EBV)-positive nasopharyngeal carcinoma (NPC) cells, but not exosomes from EBV-negative NPC cells, destroyed endothelial cell tight junction proteins, which are natural barriers against metastasis, and promoted endothelial-to-mesenchymal transition in endothelial cells.