cell reprogramming

[Nature] The authors demonstrated, by creating an intermediate plastic state, the chemical reprogramming of human somatic cells to human chemically iPSCs that exhibited key features of ESCs.

[Bone Research] Scientists summarize the latest research progress on two aspects of spinal cord injury pathology: intraneuronal microenvironment imbalance and regenerative microenvironment imbalance.

[Science Advances] The authors used genome-wide screening to identify essential regulators as well as major impediments of human primed to naïve PSC reprogramming.

[Heliyon] Scientists reported that depletion of Jmjd6 not only resulted in downregulation of pluripotency genes, but was also implicated in apoptosis, glycolysis, cell cycle and protein hydroxylation.

[Advanced Science] The authors reported a robust method to convert fibroblasts to neurons through targeting the cytoskeleton followed by exposure to lineage-specification surroundings.

[American Journal of Physiology-Cell Physiology] The authors discuss the latest research on long non-coding RNAs in iPSC stemness, neuronal, and cardiac differentiation.