caspase-3

[Food and Chemical Toxicology] Researchers studied the photosensitization potential and mechanism involved in dermal phototoxicity of 2,4,5,6-tetraaminopyrimidine sulfate exposed to the dark and UVA/UVB/Sunlight by using different in-chemico and mammalian HaCaT cells, as test systems.

[Life Sciences] The role of multiple epidermal growth factor like domains 11 (MEGF11) was studied in human TNBC MDA-MB-231 and MDA-MB-468 cells by overexpressing MEGF11 using non-attached culture.

[Immunopharmacology and Immunotoxicology] Scientists investigated the effects of miR-222-3p on the formation of medulloblastoma stem-like cells via the Notch2/c-myc pathway.

[Scientific Reports] Cell viability assay revealed that apiin, rhoifolin, and vitexin could inhibit proliferation of PANC-1 and ASPC-1, with rhoifolin showing the maximum inhibitory effect.

[Journal of Biochemical and Molecular Toxicology] Scientists delineated the role of gymnemic acid in protecting pancreatic β-cells in diabetic animals, with special reference to inflammation and apoptosis.

[Anti-Cancer Drugs] Scientists investigated whether the novel factor 3,5-dihydroxy-4-methoxybenzyl alcohol, suppressed the activity of metastatic human prostate cancer PC-3 or DU-145 cells.