cancer stem cells

[Cancer Research] Researchers reported that Rab13, a small GTPase, is highly expressed in breast CSCs.

[Biomedicine & Pharmacotherapy] Sphaerococcenol A capacity to impact colorectal-CSCs tumorspheres was evaluated by determining tumorspheres viability, number, and area, as well as the proteasome inhibitory activity.

[Critical Reviews in Eukaryotic Gene Expression] Significant genes associated hepatocellular carcinoma stemness features were screened through weighted gene co-expression network analysis and were functionally annotated using enrichment analysis.

[Cellular Oncology] Scientists investigated signaling cascades of B cell lymphoma 6 (BCL6) in the CSC compartment of triple negative breast cancers, and the mechanisms that govern its activity, mainly through Notch signaling.

[Journal of Cancer] Investigators showed that miR-145-5p, a recently discovered miRNA, was expressed at low levels in primary glioma stem cells.

[Frontiers in Pharmacology] Enrichment of cancer stem cells was observed in neurospheres by FACS using CD133 antibody and RT-PCR.