adipocytes

[European Journal of Nutrition] Investigators screened the actions of botanical extracts intended for oral use on human adipose tissue, using an in vitro screening model combining human intestinal cells with human adipose cells.

[Cell Death & Disease] Treatment of PDAC cells with AdipoRon led to mitochondrial uncoupling and loss of ATP production. Concomitantly, AdipoRon-treated cells increased glucose uptake and utilization.

[Scientific Reports] The authors proposed that activin A signaling could be relevant to the acceleration of visceral adipose tissue wasting in PDAC-associated cachexia.

[Food and Chemical Toxicology] The authors described a ten-day long adipogenesis model using high content analysis readouts for adipocyte number, size, and lipid content on primary human MSC sensitive enough to compare bisphenol A derivatives quantitatively in a robust and high throughput manner.

[Scientific Reports] In vitro and in vivo experiments showed that the expression of adiponectin was decreased and the expression of Il6 and Tnf was increased in the nerve-crushed group compared to that in the control group.

[Medical Oncology] Scientists assessed adipogenic differentiation and its effect on the proliferation and stemness markers in CD44+ oral squamous cell carcinoma (OSCC) CSCs. D44+ CSCs were sorted by magnetic sorting from the single-cell suspension of the OSCC tumor.