acute lung injury

[Bioengineered] Researchers indicated that circ_0001679/miR-338-3p/MAPK1 axis may play an important role in the pathogenesis of acute lung injury.

[Cell Reports] The authors identified an interferon-γ-regulated subset of monocytes, CCR2+ monocytes, as a driver of lung damage during influenza A virus infection.

[Cellular and Molecular Life Sciences] Investigators describe the origins, pathogenesis, and clinical features of COVID-19 and the potential uses of MSCs in therapeutic treatments for severe acute respiratory syndrome coronavirus 2-infected patients.

[Immunological investigations] CircRNA paralemmin 2 modulated lipopolysaccharide-caused murine lung epithelial cell injury by the microRNA-330-5p (miR-330-5p)/rho-associated coiled-coil containing protein kinase 2 (ROCK2) pathway, providing a therapeutic target for acute lung injury.

[Aging and Disease] The authors discuss the underlying pathogenesis of irreversible pulmonary fibrosis as well as preclinical disease models, and also suggest directions for future studies.

[American Journal of Respiratory and Critical Care Medicine] Human and mouse model bronchoalveolar lavage fluid samples were analyzed for the presence and activity of cathepsin S and its endogenous inhibitors.