acute lung injury

[Human Vaccines & Immunotherapeutics] Scientists investigated the effects of CYNK-001, human placental hematopoietic stem cell derived NK cells that exhibited strong cytolytic activity against a range of malignant cells and expressed high levels of activating receptors, against influenza A virus infections.

[Journal of Tissue Engineering and Regenerative Medicine] The authors present the current landscape of the field and highlights some interesting findings on MSC-derived extracellular vesicles in the context of COVID-19, including in silico, in vitro, in vivo and case reports.

[Journal of innate Immunity] Extracellular vesicles released during acute lung injury originated from alveolar epithelial cells, macrophages, and neutrophils and carry a diverse array of lipid mediators derived from ω-3 and ω-6 polyunsaturated fatty acids.

[Free Radical Biology and Medicine] Scientists investigated the important role and mechanism of C3a in preventing the occurrence of pyroptosis to protect the lung endothelial cells in sepsis-induced acute lung injury.

[Nature Communications] Researchers demonstrated that an anticorisin monoclonal antibody ameliorated lung fibrosis by significantly inhibiting acute exacerbation in the human transforming growth factorβ1 model and acute lung injury in the bleomycin model.

[Science Signaling] In human pulmonary aortic endothelial cells,lipopolysaccharide (LPS) induced decreased in the amounts of endothelial nitric oxide synthase, thrombomodulin, and vascular endothelial–cadherin, which was blocked by treatment with UNC2250.