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WJ-MSCs

Characterization of Bone Marrow and Wharton’s Jelly Mesenchymal Stromal Cells Response on Multilayer Braided Silk and Silk/PLCL Scaffolds for Ligament Tissue Engineering

[Polymers] Different scaffold configurations were characterized in terms of morphology and a mechanical response, and their interactions with two types of stem cells and bone marrow MSCs were assessed.

Ethionamide Preconditioning Enhances the Proliferation and Migration of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells

[International Journal of Molecular Sciences] Preconditioning with ethionamide promoted the proliferation of Wharton’s jelly-derived MSCs by activating phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase/extracellular signal-regulated protein kinase kinase (MEK)/extracellular signal-regulated kinase 1/2 signaling.

Clinical Effects of Intrathecal Administration of Expanded Wharton Jelly Mesenchymal Stromal Cells in Patients with Chronic Complete Spinal Cord Injury: A Randomized Controlled Study

[Cytotherapy] Patients were randomly assigned to receive a single dose of intrathecal ex vivo-expanded Wharton's jelly-MSCs from human umbilical cord or placebo and were then switched to the other arm at six months.

Xeno-Free Condition Enhances Therapeutic Functions of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells against Experimental Colitis by Upregulated Indoleamine 2,3-Dioxygenase Activity

[Journal of Clinical Medicine] Researcchers extensively compared the physiological functions of human Wharton’s jelly-derived mesenchymal stem cells in a xeno-free medium and a medium containing 10% fetal bovine serum.

Comparative Proteomic Analysis Identifies EphA2 as a Specific Cell Surface Marker for Wharton’s Jelly-Derived Mesenchymal Stem Cells

[International Journal of Molecular Sciences] A proteomic approach was employed to identify specific proteins differentially expressed by wharton's jelly derived-MSCs in comparison to those by neonatal foreskin and adult skin fibroblasts.

Anti-Fibrotic Effect of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells on Skeletal Muscle Cells, Mediated by Secretion of MMP-1

[International Journal of Molecular Sciences] In two–five-month-old mdx mice intravenously injected with 1 × 105 Wharton’s jelly-derived mesenchymal stem cells, fibrosis intensity and accumulation of calcium/necrotic fibers were significantly decreased.

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