WJ-MSCs

[Free Radical Biology and Medicine] Western blot analysis, flow cytometry, and MitoSOX staining revealed that hyperglycemia-induced mitochondrial oxidative stress production and apoptosis were attenuated in CHIP-overexpressing Wharton's jelly-derived mesenchymal stem cells

[Stem Cell Reviews and Reports] Researchers characterized and compared MSCs from three regions of the umbilical cord: Wharton’s Jelly, the perivascular space and the umbilical membrane.

[Journal of Ethnopharmacology] Proliferation of Wharton's jelly MSCs treated with Piper longum L. fruit extract was assessed by MTT assay and Cell Cycle Analysis. Effect of Piper longum L. preconditioning on osteogenic differentiation was performed.

[Stem Cell Research & Therapy] Two kinds of Wharton's jelly-MSCs were applied to evaluate their chondrogenic potential in vitro through inducing chondrogenic differentiation as the first step of our strategy, one from newborns with intrauterine growth retardation (IUGR) and the other from normal newborns but treated with excessive cortisol during differentiation to simulate the excessive maternal glucocorticoid in the IUGR newborns.

[Experimental Eye Research] Scientists evaluated the effect of the conditioned medium secreted by human Wharton's jelly MSCs (WJMSCs-CM) on the proliferation and apoptosis gene expression of the retinal pigmented epithelium.

[Biochemical Pharmacology] The authors used rat liver-derived hepatocytes injured by CCl4 treatment in co-culture system with Vitamin E pretreated-Wharton’s jelly-derived MSCs (WJMSCs) to evaluate the hepatoprotective effect of vitamin E-WJMSCs.