VEGF

[Bioorganic Chemistry] Investigators evaluated the ability of pigment C-phycocyanin to bind to the main cellular targets related in the progression of melanoma through molecular docking, and the reflection of this bind in the biological effects in the B16F10 cell line through in vitro analysis.

[Prostate] Investigators analyzed the carcinogenetic potential of exposure to GHRH of a nontumor human prostate epithelial cell line (RWPE-1) as well as its transforming effect in a xenograft model.

[Stem Cell Research & Therapy] In a wound healing mouse model, the histological evaluation of wound tissue in PBS, bone marrow MSCs (BMSCs), and ascorbic acid 2-glucoside-treated BMSCs group were investigated.

[Journal of Nanobiotechnology] VEGF/nerve growth factor (NGF)-nanoparticles (NPs) promoted VEGF and NGF co-expression simultaneously, eliminated excessive H2O2, strengthened reactions between SH-SY5Ys and HUVECs, and finally enhanced migration, tube formation, proliferation and H2O2 damage resistance of HUVECs.

[Acta Pharmacologica Sinica] Researchers investigated whether sotagliflozin, an anti-hyperglycemia SGLT2 inhibitor, exerted therapeutic angiogenesis effects in diabetic HLI in vitro and in vivo.

[Communications Biology] Researchers explored the metabolic reprogramming relevant to lung adenocarcinoma metastasis and decoded the underlying intercellular alterations.