STAT5

[Cell Reports] Investigators showed that HIV-1 cell-to-cell spread permited efficient, productive infection of resting memory T cells without prior activation.

[Cell Reports] Investigators showed that HIV-1 cell-to-cell spread permited efficient, productive infection of resting memory T cells without prior activation.

[Endocrinology] The authors addressed the species specificity of growth hormone (GH)-GH receptor activity by investigating GH actions in prostate cancer cell lines derived from a mouse Pten deletion model.

[Cell Death Discovery] Scientists found that specific deletion of Cbl-b and c-Cbl in CD11c+ cells, predominantly in dendritic cells (DCs), led to liver fibrosis, cirrhosis, and accumulation of systemic conventional Type I DCs due to enhanced cell proliferation and decreased cell apoptosis.

[Clinical Cancer Research] The combination of crenolanib and sorafenib was tolerable with antileukemic activities and rare emergence of FLT3-TKD mutations, which warrants further investigation.

[Science Advances] Investigators revealed that CCRL2 was up-regulated in primitive cells from patients with myelodysplastic syndrome and secondary AML.