MTOR

[Cell Death & Disease] The biological effects of nuclear receptor subfamily 2 group F member 1 antisense RNA 1 (NR2F1-AS1) and NR2F1 in pancreatic cancer were investigated by in vitro and in vivo experiments.

[Experimental and Molecular Medicine] Researchers investigated the role of hepatic Sestrin2 in cholestatic liver injury and its underlying mechanisms using in vivo and in vitro approaches.

[Bioscience Reports] Scientists showed that alanine serine cysteine‑preferring transporter 2 (ASCT2) expression was significantly higher in pancreatic cancer than in normal pancreatic duct cells and pancreas.

[Molecular Cancer Research] Pharmacologic inhibition of mTOR kinase by Torin2 significantly sensitized lung squamous cell carcinoma cell lines to ionizing radiation.

[Molecular Therapy] Investigators screened LINC01234 as an aspartate metabolism-related lncRNA in HCC. Clinically, LINC01234 was highly expressed in HCC, and high LINC01234 expression level was correlated with poor prognosis of HCC patients.

[Human Cell] Scientists investigated the antifibrosis effects of exosomes by focusing on miRNAs. Myocardial fibrosis was induced in rats using transverse aortic constriction method and handled with exosomes from bone MSCs.