GFAP

[Scientific Reports] Scientists investigated the effect of extracellular vesicles derived from human umbilical cord-MSC on the clinical score and inflammatory/anti-inflammatory cytokines on the EAE mouse model.

[Scientific Reports] Researchers silenced Ndufs4 in Neuro-2a cells and we observed shorter neurite lengths with decreased expression of synaptophysin.

[Cell Death & Disease] Scientists generated 2D and 3D in vitro human FXS model systems based on isogenic fragile X mental retardation protein knock-out mutant and wild-type human induced pluripotent stem cell (hiPSC) lines.

[NPG Asia Materials] Researchers established an in vitro model to assess the responses of astrocytes to matrix stiffness changes that may be related to pathophysiology.

[npj Parkinsons Disease] In cell lines derived from Parkinson’s disease patients, astrocytes were characterized by a significant decrease in S100B and GFAP-positive astrocytic profiles associated with marked decrease in astrocyte complexity.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers showed that glial fibrillary acidic protein (GFAP) was readily palmitoylated in vitro and in vivo; specifically, cysteine-291 was the unique palmitoylated residue in GFAP.