Bcl-2

[Journal of Biochemical and Molecular Toxicology] Scientists delineated the role of gymnemic acid in protecting pancreatic β-cells in diabetic animals, with special reference to inflammation and apoptosis.

[Scientific Reports] Investigators explored the potential alleviating effects of dietary nano-supplement combined with bacillus strains in colitis a model.

[Scientific Reports] The authors investigated the potential benefit of LCZ696, an angiotensin receptor–neprilysin inhibitor against doxorubicin-induced cardiotoxicity in rats and H9c2 cells and determined whether the mechanism underlying any such effects involved its antioxidant activity.

[Cell Death & Disease] Scientists reported the role of Lon in the response to cisplatin-induced mtDNA damage and oxidative stress, which conferred cancer cells on cisplatin resistance via modulating calcium levels in mitochondria and cytosol.

[Journal of Photochemistry and Photobiology B-Biology] Researchers found that blue light-induced oxidative stress triggered the endoplasmic reticulum stress-C/EBP homologous protein signal and affected the protein levels of B-cell lymphoma-2 (Bcl-2) and Bcl2-associated X, thereby promoting apoptosis.

[Chemistry & Biodiversity] Related substances of synthesized polyphenolic compounds 4 and 5 effects on prostate cell viability were evaluated by MTT analysis, and their effects on migration were examined by in vitro scratch analysis.