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B cells
Immune Regulation News
A Guide to Antigen Processing and Presentation
[Nature Reviews Immunology] Scientists describe the essentials of antigen processing and presentation and how the source proteins for these antigens are tagged for degradation, destroyed and ultimately displayed as peptides in complex with major histocompatibility complex molecules for T cell recognition.
Mesenchymal Cell News
Menstrual Blood-Derived Mesenchymal Stromal Cells Efficiently Ameliorate Experimental Autoimmune Encephalomyelitis by Inhibiting T Cell Activation in Mice
[Stem Cell Research & Therapy] Researchers evaluated the therapeutic potential of MSCs isolated from menstrual blood as ready-to-use allo-MSCs in multiple sclerosis by application in its animal model experimental autoimmune encephalomyelitis.
Immune Regulation News
Ubiquitin-Like Protein 3 (UBL3) Is Required for MARCH Ubiquitination of Major Histocompatibility Complex Class II and CD86
[Nature Communications] Researchers showed, using a genome-wide CRISPR knockout screen, that UBL3 was a necessary component of ubiquitination-mediated trafficking of major histocompatibility complex class II and CD86 in mice and in humans.
Immunology of Infectious Disease News
Transient Viral Exposure Drives Functionally-Coordinated Humoral Immune Responses in HIV-1 Post-treatment Controllers
[Nature Communications] Scientists performed comprehensive immunoprofiling of the humoral response to HIV-1 in long-term post-treatment controllers.
Immune Regulation News
Ubiquitin-Like Protein 3 (UBL3) Is Required for MARCH Ubiquitination of Major Histocompatibility Complex Class II and CD86
[Nature Communications] Researchers showed, using a genome-wide CRISPR knockout screen, that UBL3 was a necessary component of ubiquitination-mediated trafficking of major histocompatibility complex class II and CD86 in mice and in humans.
Immunology of Infectious Disease News
Transient Viral Exposure Drives Functionally-Coordinated Humoral Immune Responses in HIV-1 Post-treatment Controllers
[Nature Communications] Scientists performed comprehensive immunoprofiling of the humoral response to HIV-1 in long-term post-treatment controllers.