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Prostate Cell News
Prostate Cell News is an online resource summarizing the latest prostate cell research.
Covalent Destabilizing Degrader of AR and AR-V7 in Androgen-Independent Prostate Cancer Cells.
[Journal of the American Chemical Society] Scientists utilized a cysteine-reactive covalent ligand library in a cellular screen to identify degraders of the androgen receptor (AR) and AR-V7 in androgen-independent prostate cancer cells.
Differentiating Aggressive from Nonaggressive Prostate Cancer Using Unconjugated Contrast Agents.
[ACS Applied Materials & Interfaces] With growing clinical interest in combining optical, ultrasound, and photoacoustic imaging approaches for cancer detection, investigators systematically explored the cellular uptake of three multimodal contrast agents across prostate cancer cell lines with varying aggressiveness.
The Additive Value of 68Ga-RM26 PET/CT to 68Ga-PSMA-617 PET/CT in Assessing Post-Treatment Outcomes of ARSIs in mCRPC Patients.
[European Journal of Nuclear Medicine and Molecular Imaging] Compared to gastrin-releasing peptide receptor - (GRPR-) patients, metastatic castration-resistant prostate cancer (mCRPC) patients with GRPR + lesions exhibited a lower median maximum PSA response rate and a shorter median progression-free survival duration following ARSI treatment, implying a poorer response to therapy and relatively worse prognosis in the latter subgroup.
Enhanced Vascular Inflammation in Patients With Advanced Prostate Cancer Receiving Hormone Therapy.
[European Journal of Nuclear Medicine and Molecular Imaging] Advanced prostate cancer patients undergoing hormone therapy demonstrate increased arterial inflammation on [18F]FDG-PET imaging compared to non-hormonally treated controls.
D-Mannose Augments Targeted Radioligand-Immunotherapy of Prostate Cancer by Enhancing Radiosensitivity and Reshaping Immune Microenvironment.
[Drug Delivery and Translational Research] Researchers found that oral medication of D-mannose effectively enhances the radiosensitivity of PSMA-positive murine RM1-hPSMA prostate cancer cells to targeted radioligand therapy by suppressing glucose metabolism.
Depletion of P2X4 Receptor Alleviates Prostate Cancer Bone Metastasis Through Reduced Cancer Cell Invasiveness and Enhanced Cell Adhesion Activities.
[Purinergic Signalling] To understand the role of P2X4 receptor (P2X4R) in prostate cancer (PCa) biology, particularly in PCa bone metastasis, P2X4R was knocked out in human PCa cell line PC3 cells using the CRISPR/Cas9 system.
Recent Advances in Drug Treatment for Prostate Cancer.
[Japanese Journal of Radiology] The authors summarize the latest drug treatment strategies and clinical concerns in the management of advanced prostate cancer in Japan, based on the Japanese Clinical Practice Guidelines for Prostate Cancer published in 2023.
Philochem AG Announces the Licensing of Worldwide Rights to OncoACP3, a Novel Radiopharmaceutical Therapeutic, and Diagnostic Agent Targeting Prostate Cancer, to RayzeBio, a Bristol-Myers...
[Philochem AG] Philochem AG announced a definitive agreement under which Philochem will license the exclusive worldwide rights to develop, manufacture, and commercialize OncoACP3, a clinical stage therapeutic and diagnostic agent targeting prostate cancer, to RayzeBio.
Transcriptional Analysis of Metastatic Hormone-NaïVe Prostate Cancer Primary Tumor Biopsies Reveals a Relevant Role for SOX11 in Prostate Cancer Cell Dissemination
[Genome Biology] Scientists provided the first extensive transcriptomics characterization of primary tumor specimens from patients with metastatic hormone-naïve prostate cancer.
Unraveling the Efficacy of AR Antagonists Bearing N-(4-(Benzyloxy)Phenyl)Piperidine-1-Sulfonamide Scaffold in Prostate Cancer Therapy by Targeting LBP Mutations
[Journal of Medicinal Chemistry] Researchers developed a compound, which contains an N-(4-(benzyloxy)phenyl)piperidine-1-sulfonamide scaffold through structural optimization and comprehensive screening against T878A-mutated androgen receptor.
Pericytes in Castration-Resistant Prostate Cancer Associated with Disease Progression and Immunotherapy Response: Insights from Single-Cell Analysis
[Cancer Cell International] Researchers decipher the biological effects of pericytes on castration-resistant prostate cancer and their interactions with the tumor microenvironment.
A Fluorescent Probe Targeting EGFR for the Stratification of Prostate Cancer Cells
[Journal of Molecular Biology] Scientists designed a competitive, modular fluorescent probe targeting the oncogenic epidermal growth factor receptor (EGFR) kinase and was utilized for probe-based cytometry to subtype urine samples from prostate cancer patients.
Published since 2010, Prostate Cell News compiles top scientific journal articles covering the characterization, behavior, and culturing of prostate cells. Additionally, our editorial team curates the latest press releases, technical advances, jobs, and events relevant to the prostate cell research community. Prostate Cell News saves scientists valuable time while keeping them informed in their field, facilitating the rapid exchange of cutting edge research updates and science news.
