Melatonin Treatment Improves Human Umbilical Cord Mesenchymal Stem Cell Therapy in a Mouse Model of Type II Diabetes Mellitus via the PI3K/AKT Signaling Pathway

Scientists investigated whether the combination of melatonin and human umbilical cord mesenchymal stem cells (hUC-MSCs) was superior to hUC-MSCs alone in ameliorating high-fat diet and streptozocin-induced type II diabetes mellitus in a mouse model.