In Vitro Function and In Situ Localization of Multidrug Resistance-Associated Protein (MRP)1 (ABCC1) Suggest a Protective Role against Methyl Mercury-Induced Oxidative Stress in the Human Placenta

The authors concluded that MRP1 protected placental cells from methyl mercury-induced oxidative stress by exporting the toxic metal and by maintaining the placental cells’ glutathione status in equilibrium.