Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer

By
Justin.choi
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0
477
Investigators showed that the mitochondrial calcium uniporter promoted pancreatic ductal adenocarcinoma cell migration, invasion, metastasis, and metabolic stress resistance by activating the Keap1-Nrf2 antioxidant program.
[Cancer Research]

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Abstract