Genetic Variation at 11q23.1 Confers Colorectal Cancer Risk by Dysregulation of Colonic Tuft Cell Transcriptional Activator POU2AF2

Researchers employed analysis of RNA sequencing, single-cell RNA sequencing, chromatin immunoprecipitation sequencing and single-cell ATAC sequencing data to identify, prioritize, and characterise the genes that contribute to colorectal cancer risk.