CCN5 Suppresses Injury-Induced Vascular Restenosis by Inhibiting Smooth Muscle Cell Proliferation and Facilitating Endothelial Repair via Thymosin β4 and Cd9 Pathway

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CCN5 exerted a dual protective effect on in-stent restenosis (ISR) by inhibiting vascular smooth muscle cell proliferation and facilitating endothelial cell repair. CCN5rp-coated stent might be promising in the prevention of ISR after percutaneous coronary intervention.
[European Heart Journal]
AbstractGraphical Abstract