IRE1α–XBP1 Safeguards Hematopoietic Stem and Progenitor Cells by Restricting Pro-Leukemogenic Gene Programs

By
Emily Salmini
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0
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Investigators uncovered unfolded protein response stress sensor inositol-requiring enzyme-1α (IRE1α) signaling in hematopoietic stem and progenitor cells as a safeguard against myeloid leukemogenesis.
[Nature Immunology]
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