Maternal Phthalates Exposure Promotes Neural Stem Cell Differentiation into Phagocytic Astrocytes and Synapse Engulfment via IRE1α/XBP1s Pathway

Scientists demonstrated that maternal exposure to monobutyl phthalate enhanced neural stem cell differentiation into astrocytes with highly expressed C3 and LCN2 in mouse offspring, resulting in increased synapse phagocytosis and cognitive dysfunction.