Crosstalk Between FTH1 and PYCR1 Dysregulates Proline Metabolism and Mediates Cell Growth in KRAS-Mutant Pancreatic Cancer Cells

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Scientists observed a direct correlation between ferritin, comprising heavy (FTH1) expression and cell viability and clonogenicity in KRAS-mutant PDAC cell lines as well as with in vivo tumor growth through the control of proline metabolism.
[Experimental & Molecular Medicine]
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